Description

Norflex is a central M-cholinoblocker and myorelaxant. It also belongs to the group of antiparkinsonian drugs.

When to take the drug

Norflex Plus is prescribed for painful muscle spasms that occur against the background of:

• tetanus;

• traumas of the musculoskeletal system;

• diseases of the musculoskeletal system.

The drug can also be prescribed for parkinsonism and arthritis. If this product does not meet your needs or interests, you may want to look at Naxadol Carisoprodol Naproxen 250 mg 30 caps. Please visit this link for further information on our Muscle Relaxers Pills

Which is stronger – Norflex or Zanaflex

Zanaflex is also a centrally acting muscle relaxant. Maximum plasma concentration occurs within 60-120 minutes.

Norflex is absorbed within 2-4 hours when taken orally. The duration of the effect of this drug varies from 4 to 6 hours.

Release and composition forms

Norflex Plus Orphenadrine is a drug to relax the muscles and relieve spasms, available as tablets for oral administration. The package contains 50 tablets. Each tablet contains 35 mg of orphenadrine and 450 mg of paracetamol.
Each component performs its own function. Orphenadrine eliminates painful sensations and returns comfort, and paracetamol enhances its action and slows the spread of the inflammatory process.

The maximum concentration of the active components is observed 2-4 hours after intake. The analgesic effect lasts up to 5-6 hours. The spent drug is excreted mainly by the kidneys with the urine.

Who the product is contraindicated

Norflex Plus is contraindicated for use in the presence of an allergic reaction to the product’s main components.

It’s not recommended to take the drug to persons with myasthenia gravis and with a history of cardiaspasm. The drug is also not accepted in case of:

• obstruction of the bladder neck;

• prostatic hypertrophy;

• stenotic ulcer;

• gastrointestinal obstruction;

• glaucoma.

During pregnancy, the drug is prescribed with great caution. This is possible only if the potential risk to the fetus is less than the expected benefits to the health of the mother.

In children, the drug is not prescribed. The drug is prescribed for elderly people with caution.

How to take the medicine

For muscle spasms, the drug is taken twice a day. The drug is injected into the muscle, or into a vein. The optimal daily dosage is 100 mg.

For parkinsonism, the drug is taken orally, three times in 24 hours. The optimal dosage is 50 mg.

Action in the body

Orphenadrine has a complex action. It works simultaneously as an anesthetic (similar to lidocaine), antihistamine (similar to diphenhydramine), and analgesic (similar to nefopam). What is the effect of the active substance on the body:

• blocks histamine and muscarinic receptors;
• inhibits sodium channels;
• regulates the reuptake system of the hormone norepinephrine.

As a result, the conduction of nerve impulses is disrupted, which leads to the alleviation of skeletal and muscular pain. The pills help to relieve pathological tension without provoking atony. Healthy muscle fibers are not affected. Additionally, the substance has a sedative and anti-allergic effect.

Paracetamol as part of the drug has a moderate anti-inflammatory and analgesic effect. It’s a safe substance that can reduce body temperature, relieve pain, accelerate the healing of soft tissues.

Overdose of the drug

The main signs of overdose are:

• painful sensations in the lower abdomen;

• decreased appetite;

• nausea, which turns into vomiting;

• the pallor of the skin.

As a consequence of a 1-time overdose, hepatic cell necrosis is likely to develop. This process may be reversible or irreversible.

In case of overdose, the victim requires immediate medical attention. The use of activated charcoal is possible. Additionally, symptomatic therapy is carried out.

If the recommended dose is exceeded, the patient develops signs of intoxication – nausea, vomiting, diarrhea. Headaches, seizures aren’t excluded. In severe cases, respiratory depression, paralysis, and renal failure may occur. Treatment of overdose is symptomatic. There is no specific antidote. In mild intoxication, gastric lavage is indicated, in severe – forced diuresis.

Admission of the drug affects the CNS. The active ingredients may cause headaches, confusion, dizziness, somnolence. Against the background of admission, concentration decreases, anxiety and restlessness develop. During treatment, it is forbidden to perform work that requires quick reactions. It’s forbidden to drive vehicles.

Possible side effects

Against the background of long-term treatment of tablets with orphenadrine in the composition may:

• allergic rashes;
• skin itching;
• tachycardia;
• rapid breathing;
• pain in the stomach;
• nausea;
• intestinal disorders;
• urinary retention;
• general weakness;
• tremors of the extremities;
• nasal congestion;
• blurred vision.

What adverse reactions occur

Frequent adverse reactions are observed on the respiratory organs. For example, a person may complain of nasal congestion.

Some people complain of increased intraocular pressure: they get a feeling that their eyeballs are “bulging”. This condition is sometimes combined with intracranial pressure. Their vision becomes blurred, and they feel as if something is floating in front of their eyes.

Sometimes nystagmus or mydriasis occurs.

Adverse reactions from the skeletal and neuromuscular systems may occur. The person complains of severe weakness in the muscles, and sometimes his hands or feet begin to tremble. The tremor may be accompanied by general weakness and mild nausea.

Some patients experience hypersensitivity reactions:

• skin itching;

• urticaria;

• sneezing (rare).

Quincke’s edema, an extremely dangerous condition requiring urgent medical attention, is also possible.

In 30-40% of cases, patients complain of problems with the genitourinary system. For example, older people may experience urinary retention.

Gastrointestinal problems may also occur in older people. Some older patients complain of mild nausea, which sometimes combines with dizziness, or turns into vomiting. Irritation of the stomach may occur. Problems with stools – such as constipation – also occur.

Norflex may also have a negative effect on the CNS. Some people complain that they have a headache after taking the medicine. Younger people become more agitated and irritable. Older patients complain of drowsiness. In severe cases, consciousness becomes confused and hallucinations appear.

Less often the drug affects the heart: patients complain of increased heartbeat.

Additional information

Due to the fact that Norflex Plus can cause dizziness and drowsiness, you should not drive after taking it. Also, do not engage in activities that require rapid psychomotor reactions and increased concentration.

If a patient takes barbiturates, anticonvulsants, and diuretics, he should get additional advice from his doctor.

The drug should be stored in the original package, in a cool and dry place out of the reach of sunlight and children and pets. The optimum temperature for storage is + 25 degrees Celsius.

In our pharmacy, you can inexpensively buy Norflex online. Delivery is made all over the country.

Norflex Plus: instructions for use. Norflex plus para que sirve?

Norflex plus is a combination drug that consists of Acetaminophen and Orphenadrine.

Acetaminophen belongs to the group of anilides, has pronounced analgesic and antipyretic properties. That is, it is an antipyretic, analgesic and anti-inflammatory agent.

Orphenadrine belongs to the group of myorelaxants of central action, reduces pathological muscle tone. It has parasympatholytic, antihistamine and local anesthetic effect.

The combination Paracetamol Orphenadrine citrate is used in the treatment of conditions such as:

• Muscle injury.
• Sprains and strains.
• Intervertebral disc prolapse.
• Neck trauma.
• Acute torticollis and other painful muscle conditions.

Dosage

Orphenadrine Paracetamol, available as regular and extended-release tablets for oral administration.

For adults: 1 to 2 tablets every 8 hours. It is important that you visit your doctor before taking this medicine, as only a specialist will be able to prescribe treatment for you according to your condition.

It is not recommended to take Norflex plus for more than 10 days. If the pain does not stop, it is important to see your doctor.

Contraindications for use

The drug is prescribed only by a doctor, as Norflex plus 450 mg has various contraindications, including:

• hypersensitivity to the components of the drug;
• recurrent nasal polyps;
• renal and hepatic insufficiency;
• acute angle glaucoma;
• diseases of the neuromuscular apparatus;
• achalasia of cardia;
• chronic bronchial diseases (bronchial asthma);
• pregnancy in the 3rd trimester;
• persons under 18 years of age;
• uncontrolled AH;
• non-specific ulcerative colitis, acute Crohn’s disease;
• people of advanced age (over 65);
• cachexic people or people with weight deficiency;
• arterial hypotension (systolic pressure level below 100 mm Hg);
• epilepsy;
• mental disorders.

This is not a complete list of contraindications for Norflex (Paracetamol Orphenadrine), so read the instructions carefully before use. This information is not an official instruction for the product and is for information purposes only.

Side effects

Norflex (Orphenadrine citrate Paracetamol) may cause side effects if the doctor’s recommendations are not followed:

1. Cardiovascular system: tachycardia, occurrence of various edemas, arterial hypertension, pain in the heart.

2. Blood and lymphatic system: thrombocytopenia, purpura, leukopenia, pancytopenia, agranulocytosis, anemia (including hemolytic and aplastic anemia), eosinophilia.

3. Nervous system: rapid fatigue; dizziness and headaches; sensory disorders (including paresthesia); memory disorders; disorientation; convulsions; anxiety; tremor; aseptic meningitis; taste disorders; stroke.

4. Visual organs: blurred vision or diplopia, sensations of dryness and pain in the eye area, temporary accommodation disorders, glaucoma.

5. Hearing organs and labyrinth disorders: vertigo, temporary hearing loss, tinnitus.

6. Respiratory system: rhinitis, asthma (including shortness of breath), pneumonia.

7. Digestive system: dry mouth, pain in the epigastric region, loss of appetite, nausea, vomiting, diarrhea, abdominal cramps, dyspepsia, anorexia, flatulence, bloating, gastritis.

8. Renal and urinary tract: urinary retention, urinary incontinence, sodium and water retention, acute renal failure, hematuria, interstitial nephritis, nephrotic syndrome, proteinuria, papillary necrosis.

9. Skin and subcutaneous tissue: urticaria, alopecia, bullous rash, eczema, erythroderma, purpura, Stevens-Johnson syndrome (erythema multiforme), Lyell syndrome, exfoliative dermatitis, photosensitivity reaction, itching.

10. Immunity: allergic reactions, decreased BP, shock and bronchospasm, angioedema (including facial edema), tongue swelling, internal laryngeal edema, including tracheal stenosis, dyspnea.

11. Liver and biliary tract: temporary increase in transaminase activity, liver failure of varying severity, hepatitis, accompanied and not accompanied by jaundice, fulminant hepatitis, liver necrosis, acute liver failure.

12. Reproductive system and mammary glands: impotence, burning in the genital area in women. 26.

13. Psychiatric disorders: euphoria, nervousness, sleep disorders, confusion, emotional lability, disorientation, depression, insomnia, anxiety, nightmares, irritability, psychotic disorders.

Side effects can be minimized by using the lowest effective dose for the shortest period. Therefore, it is important to follow your doctor’s orders and not exceed the recommended dose of the drug.

If you drink alcohol, consult your doctor before you start taking Norflex (Orphenadrine citrate Paracetamol)

This medicine and alcohol are incompatible and put more strain on your liver and kidneys, which can lead to serious consequences.

Overdose

Symptoms:

Paracetamol. Abuse of Paracetamol can cause a number of serious problems for the body, but the most dangerous thing is that in the first 24 hours of overdose may be asymptomatic. Later, typical symptoms of poisoning, such as nausea, dizziness, and within 72 hours after overdose, abdominal pain with unclear localization appear. After 4-5 days, the failure of the body manifests itself fully in the form of acute liver failure.

Toxic is considered already 10 g of the substance (or 150-200 mg per 1 kg of human body weight), suggests a high chance of hepatotoxicity (liver damage) up to lethal outcome.

Treatment

If an excessive dose of Acetaminophen has been ingested within 1 hour, it is worth taking an absorbent agent. Plasma concentrations are measured 4 to 6 hours after ingestion.

N – Acetylcysteine can be used 24 hours after taking Acetaminophen, but the greatest productive effect can be achieved within 8 hours of use. The potency of the antidote decreases significantly after this time. Sometimes there is a need for intravenous administration of N – Acetylcysteine.

If there are no signs of vomiting, Methionine may be administered orally. The doctor may also prescribe symptomatic treatment.

Symptoms:

Orphenadrine. In an acute overdose of Orphenadrine, the symptoms are found:

• hot, dry skin; profuse sweating; redness of the face, dry mucous membranes; increased respiratory rate;
• dilated pupils; motor disorders; muscle tremors; ataxia; tonic and clonic convulsions;
• hallucinations, anuria; abnormal heart rhythm; heart failure; fatigue;
• collapse; unconsciousness and impaired electrolyte and acid-base balance.

Treatment:

In case of overdose, indicated:

• forced diuresis to obtain a large volume of urine;
• peritoneal dialysis, hemodialysis;
• supportive therapy, such as intravenous fluids and measures to regulate circulation, depending on symptomatology.

For choline-blocking effects caused by Orphenadrine, treatment with Physostigmine may be tried.

Buy Wholesale Norflex Plus Orphenadrine From Mexican Pharmacy Store

At Mexican Pharmacy Store, our products are of the highest quality. Our Norflex Plus Orphenadrine For Sale comes in 35 mg of orphenadrine and 450 mg of paracetamol (50 Tablets). We’re passionate about our products, and we always strive to provide our customers with the best in both selection and quality. All of the products we provide are tested to verify authenticity and match up with regulatory standards, so you can carry out your health treatment with confidence.

Searching for Norflex Plus Orphenadrine for sale? Look no further! Our online mexican pharmacy store offers a wide range of Norflex Plus Orphenadrine, perfect for your medical needs. Whether you’re in the United States, Mexico,Canada, Spain, Denmark, Australia, France, Belgium, Italy, Netherlands or the United Kingdom, we have you covered.

We provide fast and secure shipping to multiple countries, ensuring that you receive your order conveniently and on time. Purchase Norflex Plus Orphenadrine that are now available for sale and in stock. With our competitive prices and extensive inventory, you can trust us to be your reliable source for Norflex Plus 50 Tabs (Paracetamol, Orphenadrine).

Want to learn more about our products or have a question about payment options? Our customer service team is here to help. Mexican Pharmacy Store provides discounts on bulk orders. So, what are you waiting for? order Norflex Plus Orphenadrine For Sale and experience first-hand quality service, prompt response and quick shipping. Stock up on the highest quality Norflex Plus Orphenadrine For Sale and more at Mexican Pharmacy Store today.