The drug Farmapram belongs to the group of anxiolytics. It is prescribed for neurosis and psychopathy, which is accompanied by an anxious, restless state. The drug is effective for depression, including if it is caused by somatic diseases. For the treatment of patients with alcoholism and drug addiction, the drug is prescribed in case of diagnosis of panic disorder or abstinence syndrome.
Composition of Farmapram (Alpazolam) 2mg
The main component of the drug alprazolam is a benzodiazepine derivative. The active substance is insoluble in water and poorly soluble in alcohol. It is available in 0.25 mg, 0.5 mg, 1 mg, and 2 mg tablets.
Farmapram Alprazolam comes in the form of tablets with the active ingredient alprazolam. There are 4 more dosage variants 0.25 mg, 0.5 mg, 1 mg, 2 mg.
Farmapram Alprazolam binds to benzodiazepine and GABAergic receptors. It affects the limbic system, thalamus, hypothalamus, polysympathetic spinal receptors, causing their inhibition. It has anxiolytic, myorelaxant, central, and sedative effects on the body.
After internal administration complete absorption occurs after 1-2 hours. Up to 80% of the substance is bound to blood plasma proteins. It penetrates through the BBB, placental barrier, and into breast milk. Metabolism in the liver takes 16 hours. Excretion of the substance occurs through the kidneys. Cumulation occurs if repeated intake is less than 8-10 hours apart.
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Administration and dosage
Farmapram Alprazolam 2mg is taken orally only. The dosage is determined individually, depending on the course of the disease, tolerance of the components. Therapy begins with a minimum dose of 0.25 to 0.5 mg, which the patient takes 3 times a day. If the drug is well tolerated every 3 – 4 days, the dose can be increased. The maximum allowable value is 3 – 4 mg.
How should you take Alprazolam?
Alprazolam may be taken with or without food. Take it exactly as prescribed. Do not chew, crush, or break the Xanax XR tablets.
If you miss a dose… If you are less than 1 hour late, take it as soon as you remember. Otherwise skip the dose and go back to your regular schedule. Never take 2 doses at the same time. Storage instructions…
Store Alprazolam at room temperature. What side effects may occur? Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Xanax. Your doctor should periodically reassess the need for Alprazolam.
Side effects of Xanax are usually seen at the beginning of treatment and disappear with continued medication. However, if dosage is increased, side effects will be more likely.
Side effects of Alprazolam may include:
Decreased libido, drowsiness, fatigue, impaired coordination, memory impairment, speech difficulties, weight changes
Side effects of Xanax XR may include:
Constipation, decreased libido, depression, drowsiness, fatigue, impaired coordination, memory problems, mental impairment, nausea, sedation, sleepiness, speech difficulties, weight changes
Side effects due to a rapid decrease in dose or abrupt withdrawal from Xanax or Xanax XR:
Anxiety, blurred vision, decreased concentration, decreased mental clarity, depression, diarrhea, headache, heightened awareness of noise or bright lights, hot flushes, impaired sense of smell, insomnia, loss of appetite, loss of reality, muscle cramps, nervousness, rapid breathing, seizures, tingling sensation, tremor, twitching, weight loss
How to use
Farmapram Xanax is prescribed only by a doctor. The dose is chosen individually. Admission begins with 250-500 mcg 3 times/day with an increase to 4.5 mg/day. Elderly patients are prescribed 250 mcg 2-3 times/day, then 500-750 mcg/day. To avoid unwanted symptoms when withdrawing the drug, the dose should be reduced gradually – 500 mcg every 3 days.
- Panic disorder, neurotic condition.
- Unreasonable anxiety, restlessness, irritability.
- Sleep disorders, frequent waking up.
- Anxiety-depressive, neurotic reactive-depressive states that are accompanied by eating and sleeping disorders.
- Agoraphobia – fear of open or public places.
- Alcohol withdrawal.
- Pain in the period before menstruation.
- Irritable bowel syndrome.
Contraindications and peculiarities of use
– Individual intolerance to the main or auxiliary components.
– Acute attack of glaucoma.
– Disorders of liver and kidney function.
– Myasthenia gravis.
– Period of pregnancy and lactation.
– Age of patients under 18 years old.
– Liver damage in alcohol dependence.
– Adverse reactions and overdose.
The main adverse reactions include impaired motor and mental reactions, which is manifested in a wobbly gait, drowsy state, dizziness. Gastrointestinal disorders are possible – constipation, nausea. Adverse reactions also include dysmenorrhea, itching on the skin. Paradoxical phenomena are manifested by aggressive reactions, anxiety, agitation and hallucinations. With constant intake, an addictive behavior occurs. Withdrawal syndrome occurs if treatment is stopped abruptly.
Farmapram 2mg should not be combined with alcohol, neuroleptics, hypnotics, and narcotic drugs because of their increased effect. May affect reactions while driving vehicles. Discontinue use if paradoxical reactions occur.
Overdose may lead to CNS depression, coma, ataxia, decreased reflexes. First aid should cause vomiting, gastric lavage. Under hypotension, norepinephrine is administered. The antidote to the drug is flumazenil. It may be administered only under hospital conditions.
- Sensitivity to components.
- Respiratory failure.
- Impaired functioning of the kidneys, liver.
- Alcoholism, alcohol poisoning.
- Glaucoma attacks.
Farmapram pill can not be combined with psychotropic, narcotic drugs, and sleeping pills. It is forbidden to take during pregnancy and lactation.
Why is Alprazolam prescribed?
Farmapram is a tranquilizer used in the short-term relief of symptoms of anxiety or the treatment of anxiety disorders. Anxiety disorder is marked by unrealistic worry or excessive fears and concerns. Anxiety associated with depression is also responsive to Xanax.
Alprazolam and the extended-release formulation, Xanax XR, are also used in the treatment of panic disorder, which appears as unexpected panic attacks and may be accompanied by a fear of open or public places called agoraphobia. Only your doctor can diagnose panic disorder and best advise you about treatment.
Some doctors prescribe Xanax to treat alcohol withdrawal, fear of open spaces and strangers, depression, irritable bowel syndrome, and premenstrual syndrome.
Most important fact about Alprazolam
Tolerance and dependence can occur with the use of Xanax. You may experience withdrawal symptoms if you suddenly stop using the drug or reduce the dosage too quickly. Withdrawal symptoms are listed under “What side effects may occur?” The drug dosage should be gradually reduced and only your doctor should advise you on how to discontinue or change your dose.
Why should Alprazolam not be prescribed?
If you are sensitive to or have ever had an allergic reaction to Xanax or other tranquilizers, you should not take Alprazolam. Also avoid Xanax while taking the antifungal drugs. Make sure that your doctor is aware of any drug reactions that you have experienced.
Do not take Alprazolam if you have been diagnosed with the eye condition called narrow-angle glaucoma.
Anxiety or tension related to everyday stress usually does not require treatment with Xanax. Discuss your symptoms thoroughly with your doctor.
Farmapram is a tranquilizer, which has 5 types of action on the central nervous system. The drug acts as an anxiolytic, sedative and hypnotic, central nervous system muscle relaxant, and also has an anticonvulsant effect. Anxiolytic activity Farmapram 2mg is expressed in the reduction of emotional tension, anxiety, unreasonable fears, improve sleep quality.
Usage and dosages
Farmapram pill is taken regardless of meals. Doses are selected depending on the manifestation of the syndromes and the course of the disease.
Treatment with the drug should start with minimum doses, gradually increasing them to the recommended ones. Increasing the dose should be carried out within a few days or even weeks.
For anxiety, or anxiety state initially, you may take 0.25 – 0.5 mg per day with subsequent increase.
Increase doses at first in the evening and then in the daytime. In depressive states and panic disorder, you have to take 3-6 mg per day. It is not recommended to increase the dose over 10 mg.
The period of treatment with the drug is from several days to three months. Cessation of treatment should be carried out gradually, not more than 0.5 mg per day. In order to prevent withdrawal syndrome, which may cause an exacerbation of anxiety and fear, the dose should be reduced every 3 days.
Farmapram is not effective in psychotic depression and hypersensitivity. Not used in pregnancy, children under 18 years of age. Requires consultation with an endocrinologist for thyroid disorders.
Ineffectiveness of the drug may occur after repeated use over several months.
Episodes of mania and hypomania have been found in association with the use of Farmapram 2 mg and 1 mg by depressed patients. The medication is not recommended for the primary treatment of psychosis.
People with galactose intolerance, lactose deficiency, or glucose-galactose malabsorption should not use Farmapram pills.
- Tremors, lack of coordination
- Changes in body weight
- Problems with the urogenital system
- Visual disturbances
- Muscle weakness
- slurred speech
- Kidney dysfunction
- Restless sleep or excessive somnolence
- Memory impairment
- Fatigue, irritability
- Hallucinations, hostility, and aggressiveness
- Change in libido
- Skin rash and itching
- Decreased blood pressure
- Laryngeal pain, chills, fever
- Decreased appetite, constipation, or upset stomach
- Dry mouth, excessive salivation
- Headache, memory loss
With prolonged use, Farmapram (Mexico) may become addictive. With abrupt withdrawal – drug dependence or mental and physiological disorders.
Contraindications to use
- Severe depression
- Acute alcohol poisoning
- Closed-angle glaucoma
- Shock or coma
- Drug sensitivity
- Chronic respiratory conditions
- Intoxication with analgesics, psychotropics, and sleeping pills
- Children under 18 years of age
- Lactation period
Farmapram has a toxic effect during pregnancy on the fetus and may lead to the development of birth defects as well as addiction in the newborn. Because the drug penetrates the breast milk, drowsiness, and difficulty feeding the newborn may occur.
Specifics of use
People with functional disorders of the kidneys and liver need to use Farmapram pills with special care. An initial dose of 0.25 mg 2-3 per day is recommended for patients over 65 years of age. The dose is gradually increased to 0.5-0.75 mg per day.
Children under 18 years of age should not be taken medication because they are very sensitive to the suppressive effects of the drug.
Since Farmapram Alprazolam is a tranquilizer, it should not be taken with other agents of similar action.
Alcoholic beverages should not be consumed during treatment. You should refrain from driving any form of transport and working with mechanisms requiring especially high attention.
Interaction with other drugs
Side effects are possible when using Farmapram with the following medicinal products:
- Dextropropoxyphene: accumulation of Alprazolam in the blood plasma may occur
- Ketoconazole, Paroxetine and Itraconazole: increases the effects of Farmapram
- Imipramine, Fluvoxamine, Fluoxetine: increases the plasma saturation of Alprazolam and may cause psychomotor disturbances and side effects
- Erythromycin – may increase the effect of Alprazole.
Farmapram Alprazolam overdose is rarely life-threatening, except when combined with other depressants. In such a case, it should be taken into account that more than one remedy was taken. Symptoms of overdose are usually manifested by drowsiness and confusion. In more serious cases, may include coma, lethargy, respiratory depression, and death.
In case of overdose, you should induce vomiting for one hour, then take activated charcoal or other sorbents. If the patient has lost consciousness, the stomach should be flushed and, if necessary, artificial respiration should be performed.
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